Close Menu
Alpha Leaders
  • Home
  • News
  • Leadership
  • Entrepreneurs
  • Business
  • Living
  • Innovation
  • More
    • Money & Finance
    • Web Stories
    • Global
    • Press Release
What's On
Mercor, a  billion AI startup, confirms it was the victim of a major cybersecurity breach

Mercor, a $10 billion AI startup, confirms it was the victim of a major cybersecurity breach

3 April 2026
Paul Krugman smacks down Trump speech with argument that  gas is ‘less than half’ of the Hormuz hit. Here’s what he’s talking about

Paul Krugman smacks down Trump speech with argument that $4 gas is ‘less than half’ of the Hormuz hit. Here’s what he’s talking about

2 April 2026
Trump wants to add nearly T to the T national debt with military budget, watchdog warns

Trump wants to add nearly $7T to the $39T national debt with military budget, watchdog warns

2 April 2026
Facebook X (Twitter) Instagram
Facebook X (Twitter) Instagram
Alpha Leaders
newsletter
  • Home
  • News
  • Leadership
  • Entrepreneurs
  • Business
  • Living
  • Innovation
  • More
    • Money & Finance
    • Web Stories
    • Global
    • Press Release
Alpha Leaders
Home » The federal government is simultaneously investing in my startup–and crippling our business with a little-known tax code provision. Only Congress can save us
News

The federal government is simultaneously investing in my startup–and crippling our business with a little-known tax code provision. Only Congress can save us

Press RoomBy Press Room31 January 20244 Mins Read
Facebook Twitter Copy Link Pinterest LinkedIn Tumblr Email WhatsApp
The federal government is simultaneously investing in my startup–and crippling our business with a little-known tax code provision. Only Congress can save us

A provision in the tax code is threatening hundreds of early-stage, research-intensive firms. Fortunately, Congress finally seems prepared to fix the problem. But lawmakers will have to act quickly to save startups like mine.

The dilemma stems from a seemingly innocuous provision in the 2017 Tax Cuts and Jobs Act, which, among many other things, adjusted Section 174 of the tax code. Previously, that section allowed businesses to deduct the full cost of their research and development (R&D) expenses in a single year.

However, starting in 2022, the new tax law changed this longstanding practice and started requiring companies to spread out the deductions over five years. This effectively raised the yearly cost of performing scientific research, since companies could no longer claim the full R&D deduction in the year that they actually spent the money.

For small startups like mine, specifically those that have received research grants from the federal government, the change poses an existential threat to the business. Here’s why.

Cellf BIO, the firm I now help lead, was founded in 2014 based on groundbreaking work in regenerative medicine. Since then, we’ve developed a bioengineered sphincter muscle that can be grown from patients’ own cells and then implanted back into their bodies to treat their fecal incontinence. Our treatment could help millions of Americans suffering from this debilitating and quality-of-life-altering condition.

With the assistance of significant federal grant money, we were able to start Phase 1 clinical trials in 2023. We’re making great progress and have successfully achieved the major milestone of the first in-human implantation of the BioSphincter. But even in the best-case scenario, it is a long road ahead to win market approval from the FDA and start earning revenue.

To support our research, we have relied on Small Business Innovation Research (SBIR) grants from the Small Business Administration (SBA) and the National Institutes of Health.

This SBA grant program functions as seed funding for promising startups that haven’t yet raised venture capital investment. And it has proven hugely successful. 23andMe, the most recognizable name in genetic testing, initially received SBIR funding.

These federal grant programs, which are earmarked exclusively for research expenses, have always counted as taxable income. Prior to 2022, that wasn’t a problem or barrier to research startups since firms could simply deduct the full cost of R&D from the equivalent amount of grant income, leaving them with no net tax liability.

In other words, the previous status quo ensured that promising startups wouldn’t be penalized for winning government grants.

But now, because of the change in expensing, they are penalized. And penalized disproportionately. Our small firm, with less than five employees, faces a six-figure tax bill under the new rule. And because we don’t yet have an FDA-approved product, we have no sales revenue. Currently, and like many other similarly situated research startup small businesses, our income and funding stream is almost entirely based on grants.

The government’s research agencies believe in our vision and are helping ensure we can make it a reality with critical grant funding. But paradoxically, the IRS wants that money back. And new grant money is not allowed to be used to pay these taxes.

So far, we’ve managed to survive–and our technology is ready for outside investment. Many other startups aren’t so fortunate. Some have just weeks of runway left.

Lawmakers have recognized how hard this would hit small, research-intensive companies–and now they finally seem poised to do something about it. House and Senate negotiators recently announced a deal that, among other reforms, would once again allow full expensing for research, as was the standard.

The clock is ticking for Congress to act. The urgency of this issue cannot be overstated. Jobs, small businesses, and tomorrow’s life-changing innovations are on the line.

Rayana Marker is the chief operating officer of Cellf BIO LLC.

More must-read commentary published by Fortune:

The opinions expressed in Fortune.com commentary pieces are solely the views of their authors and do not necessarily reflect the opinions and beliefs of Fortune.

Subscribe to the new Fortune CEO Weekly Europe newsletter to get corner office insights on the biggest business stories in Europe. Sign up for free.
Commentary Congress Health politics Startups Taxes
Share. Facebook Twitter Pinterest LinkedIn Tumblr Email Copy Link

Related Articles

Mercor, a  billion AI startup, confirms it was the victim of a major cybersecurity breach

Mercor, a $10 billion AI startup, confirms it was the victim of a major cybersecurity breach

3 April 2026
Paul Krugman smacks down Trump speech with argument that  gas is ‘less than half’ of the Hormuz hit. Here’s what he’s talking about

Paul Krugman smacks down Trump speech with argument that $4 gas is ‘less than half’ of the Hormuz hit. Here’s what he’s talking about

2 April 2026
Trump wants to add nearly T to the T national debt with military budget, watchdog warns

Trump wants to add nearly $7T to the $39T national debt with military budget, watchdog warns

2 April 2026
Apollo and FC Barcelona just proved legacy markets are losing their grip on business

Apollo and FC Barcelona just proved legacy markets are losing their grip on business

2 April 2026
Why American billionaires are abandoning Wall Street for English soccer clubs

Why American billionaires are abandoning Wall Street for English soccer clubs

2 April 2026
Trump ousts Pam Bondi as attorney general

Trump ousts Pam Bondi as attorney general

2 April 2026
Don't Miss
Unwrap Christmas Sustainably: How To Handle Gifts You Don’t Want

Unwrap Christmas Sustainably: How To Handle Gifts You Don’t Want

By Press Room27 December 2024

Every year, millions of people unwrap Christmas gifts that they do not love, need, or…

Walmart dominated, while Target spiraled: the winners and losers of retail in 2024

Walmart dominated, while Target spiraled: the winners and losers of retail in 2024

30 December 2024
Moltbook is the talk of Silicon Valley. But the furor is eerily reminiscent of a 2017 Facebook research experiment

Moltbook is the talk of Silicon Valley. But the furor is eerily reminiscent of a 2017 Facebook research experiment

6 February 2026
Stay In Touch
  • Facebook
  • Twitter
  • Pinterest
  • Instagram
  • YouTube
  • Vimeo
Latest Articles
Why American billionaires are abandoning Wall Street for English soccer clubs

Why American billionaires are abandoning Wall Street for English soccer clubs

2 April 20261 Views
Trump ousts Pam Bondi as attorney general

Trump ousts Pam Bondi as attorney general

2 April 20261 Views
Meet China’s AI-powered recycling robot that sorts 220 pounds of clothes in 2 to 3 minutes

Meet China’s AI-powered recycling robot that sorts 220 pounds of clothes in 2 to 3 minutes

2 April 20260 Views
I knew about North Korean hackers—they still tricked me and got into my computer

I knew about North Korean hackers—they still tricked me and got into my computer

2 April 20260 Views

Recent Posts

  • Mercor, a $10 billion AI startup, confirms it was the victim of a major cybersecurity breach
  • Paul Krugman smacks down Trump speech with argument that $4 gas is ‘less than half’ of the Hormuz hit. Here’s what he’s talking about
  • Trump wants to add nearly $7T to the $39T national debt with military budget, watchdog warns
  • Apollo and FC Barcelona just proved legacy markets are losing their grip on business
  • Why American billionaires are abandoning Wall Street for English soccer clubs

Recent Comments

No comments to show.
About Us
About Us

Alpha Leaders is your one-stop website for the latest Entrepreneurs and Leaders news and updates, follow us now to get the news that matters to you.

Facebook X (Twitter) Pinterest YouTube WhatsApp
Our Picks
Mercor, a  billion AI startup, confirms it was the victim of a major cybersecurity breach

Mercor, a $10 billion AI startup, confirms it was the victim of a major cybersecurity breach

3 April 2026
Paul Krugman smacks down Trump speech with argument that  gas is ‘less than half’ of the Hormuz hit. Here’s what he’s talking about

Paul Krugman smacks down Trump speech with argument that $4 gas is ‘less than half’ of the Hormuz hit. Here’s what he’s talking about

2 April 2026
Trump wants to add nearly T to the T national debt with military budget, watchdog warns

Trump wants to add nearly $7T to the $39T national debt with military budget, watchdog warns

2 April 2026
Most Popular
Apollo and FC Barcelona just proved legacy markets are losing their grip on business

Apollo and FC Barcelona just proved legacy markets are losing their grip on business

2 April 20261 Views
Why American billionaires are abandoning Wall Street for English soccer clubs

Why American billionaires are abandoning Wall Street for English soccer clubs

2 April 20261 Views
Trump ousts Pam Bondi as attorney general

Trump ousts Pam Bondi as attorney general

2 April 20261 Views

Archives

  • April 2026
  • March 2026
  • February 2026
  • January 2026
  • December 2025
  • November 2025
  • October 2025
  • September 2025
  • August 2025
  • July 2025
  • June 2025
  • May 2025
  • April 2025
  • March 2025
  • February 2025
  • January 2025
  • December 2024
  • November 2024
  • October 2024
  • September 2024
  • August 2024
  • July 2024
  • June 2024
  • May 2024
  • April 2024
  • March 2024
  • February 2024
  • January 2024
  • December 2023
  • March 2022
  • January 2021
  • March 2020
  • January 2020

Categories

  • Blog
  • Business
  • Entrepreneurs
  • Global
  • Innovation
  • Leadership
  • Living
  • Money & Finance
  • News
  • Press Release
© 2026 Alpha Leaders. All Rights Reserved.
  • Privacy Policy
  • Terms of use
  • Advertise
  • Contact

Type above and press Enter to search. Press Esc to cancel.